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Notice of Nominees for Directors

TOKYO, April 27, 2026 – Astellas Pharma Inc. (TSE: 4503, President and CEO: Naoki Okamura, “Astellas”) today announced that at a meeting of its Board of Directors held today, it decided a change in Directors as stated below. This change is subject to approval at the 21st Term Annual Shareholders Meeting and a decision at the Board of Directors meeting, both scheduled on June 19, 2026.

1. Candidates for Directors (excluding Directors who Are Audit & Supervisory Committee Members)

Name   Current Position
Kenji Yasukawa Reelection Representative Director, Chairman of the Board
Naoki Okamura Reelection Representative Director, President and CEO
Katsuyoshi Sugita Reelection Representative Director, Executive Vice President, Chief People Officer
Masahiro Miyazaki Outside
Reelection
Outside Director, Kurita Water Industries Ltd.
Yoichi Ohno Outside
Reelection
Visiting Professor, Social Medicine, Research Administration Center and Medical Education Center, Saitama Medical University
Andreas Busch Outside 
Reelection
None
Mark Enyedy Outside 
Reelection
Non-Executive Director, BioMarin Pharmaceutical Inc.
Non-Executive Director, Charles River Laboratories International, Inc.

The current position of the candidates for outside Directors describes significant concurrent positions at other organizations pursuant to the Companies Act.

2. Candidates for Directors who Are Audit & Supervisory Committee Members

Name   Current Position
Rika Hirota Reelection Director, Full-time Audit & Supervisory Committee Member
Tomoko Aramaki Outside 
Reelection
President, Aramaki CPA Office
Outside Director, EXEO Group, Inc.
Outside Director, Audit & Supervisory Committee Member, TRE HOLDINGS CORPORATION
Shigeki Takahara Outside
New Candidate
None

The current position of the candidates for outside Directors describes significant concurrent positions at other organizations pursuant to the Companies Act.

3. Retiring Directors

Outside Director Takashi Tanaka
Outside Director Eriko Sakurai
Outside Director, Audit & Supervisory Committee Member Mika Nakayama

 

4. The Board of Directors as from June 19, 2026 (planned)

Kenji Yasukawa (Representative Director, Chairman of the Board)
Naoki Okamura (Representative Director, President and CEO)
Katsuyoshi Sugita (Representative Director, Executive Vice President)
Masahiro Miyazaki (Outside Director)
Yoichi Ohno (Outside Director)
Andreas Busch (Outside Director) 
Mark Enyedy (Outside Director)
Rika Hirota (Director, Audit & Supervisory Committee Member)
Rie Akiyama (Outside Director, Audit & Supervisory Committee Member)
Tomoko Aramaki (Outside Director, Audit & Supervisory Committee Member)
Shigeki Takahara (Outside Director, Audit & Supervisory Committee Member)

<Reference>
Brief Biographies of New Candidates for Director, Audit & Supervisory Committee Member

Name: Shigeki Takahara
Date of birth: November 12, 1958
Resume, position and responsibilities at the Company:

April 1981 Joined NEC Corporation
July 1998 Senior Manager, Corporate Finance & IR Division, NEC Corporation
March 2005 Director, Field Accounting, Pfizer Japan Inc.
December 2006 Operating Officer, Head of President Office, SSP Co., Ltd.
June 2007 Corporate Officer, CFO, MISUMI Group Inc.
January 2009 Director, CFO, Accounting & Finance Lead, Wyeth K.K. (current Pfizer Japan Inc.)
February 2011 Director and Operating Officer, CFO, Accounting & Finance Lead, Pfizer Japan Inc. (resigned in February 2020)
April 2020 Managing Executive Officer, General Manager, Corporate Planning & Finance, Kansai Paint Co., Ltd.
June 2021 Director, Senior Managing Executive Officer, Chief of Corporate Planning, Finance, HR & Administration, Kansai Paint Co., Ltd.
April 2022 Representative Director, Vice President Executive Officer, Chief of Corporate Planning, Finance, HR & Administration, Kansai Paint Co., Ltd.
April 2024 Representative Director, Vice President Executive Officer and Chief Financial Officer, Kansai Paint Co., Ltd.
July 2025 Corporate Advisor, Kansai Paint Co., Ltd. (present post)


About Astellas
Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at www.astellas.com

Cautionary Notes
In this press release, statements made with respect to current plans, estimates, strategies and beliefs and other statements that are not historical facts are forward-looking statements about the future performance of Astellas. These statements are based on management’s current assumptions and beliefs in light of the information currently available to it and involve known and unknown risks and uncertainties. A number of factors could cause actual results to differ materially from those discussed in the forward-looking statements. Such factors include, but are not limited to: (i) changes in general economic conditions and in laws and regulations, relating to pharmaceutical markets, (ii) currency exchange rate fluctuations, (iii) delays in new product launches, (iv) the inability of Astellas to market existing and new products effectively, (v) the inability of Astellas to continue to effectively research and develop products accepted by customers in highly competitive markets, and (vi) infringements of Astellas’ intellectual property rights by third parties.
Information about pharmaceutical products (including products currently in development) which is included in this press release is not intended to constitute an advertisement or medical advice.

Contacts for inquiries or additional information:
Astellas Pharma Inc.
Corporate Communications
+81-3-3244-3201