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Notice Regarding Revision of Financial Forecasts for FY2025

TOKYO, February 4, 2026 – Astellas Pharma Inc. (TSE: 4503, President and CEO: Naoki Okamura, “Astellas”) today announced upward revisions to its consolidated financial forecast for the fiscal year ending March 31, 2026 (FY2025), originally announced on October 30, 2025 (Core basis and Full basis), as follows.

1.  Revision of Financial Forecasts:

<Core basis> (Millions of yen)
  Revenue Core operating profit Core Profit for the year Basic core earnings per share (yen)
Previous
forecast(A)
2,030,000 490,000 365,000 203.79
Revised
forecast(B)
2,100,000 520,000 385,000 214.95
Change(B-A) 70,000 30,000 20,000 -
Change(%) 3.4 6.1 5.5 -
(Ref.)
Actual fiscal year 2024
1,912,323 392,435 295,682 165.17

 

<Full basis>  (Millions of yen)
  Revenue Operating profit Profit before tax Profit for the year Profit attributable to owners of the parent Basic earnings per share(yen)
Previous
forecast(A)
2,030,000 240,000 230,000 180,000 180,000 100.50
Revised
forecast(B)
2,100,000 340,000 330,000 250,000 250,000 139.58
Change(B-A) 70,000 100,000 100,000 70,000 70,000 -
Change(%) 3.4 41.7 43.5 38.9 38.9 -
(Ref.)
Actual fiscal year 2024
1,912,323 41,039 31,237 50,747 50,747 28.35

 

2. Reason for Revision:
Due to the strong global sales trend of XTANDI™ (enzalutamide) for prostate cancer and BETANIS™ / MYRBETRIQ™ / BETMIGA™ (Mirabegron) for overactive bladder, along with foreign exchange impacts, Astellas upwardly revised its business forecasts announced in October 2025.

About Astellas
Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at. www.astellas.com.

Cautionary Notes
In this press release, statements made with respect to current plans, estimates, strategies and beliefs and other statements that are not historical facts are forward-looking statements about the future performance of Astellas. These statements are based on management’s current assumptions and beliefs in light of the information currently available to it and involve known and unknown risks and uncertainties. A number of factors could cause actual results to differ materially from those discussed in the forward-looking statements. Such factors include, but are not limited to: (i) changes in general economic conditions and in laws and regulations, relating to pharmaceutical markets, (ii) currency exchange rate fluctuations, (iii) delays in new product launches, (iv) the inability of Astellas to market existing and new products effectively, (v) the inability of Astellas to continue to effectively research and develop products accepted by customers in highly competitive markets, and (vi) infringements of Astellas’ intellectual property rights by third parties. Information about pharmaceutical products (including products currently in development) which is included in this press release is not intended to constitute an advertisement or medical advice.

Contacts for inquiries or additional information:
Astellas Pharma Inc.
Communications and Investor Relations
+81-3-3244-3201